1273148-19-8Relevant articles and documents
Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H- pyrrol-3-yl]phenylmethanone. the effect of methoxy substitution on aldose reductase inhibitory activity and selectivity
Chatzopoulou, Maria,Mamadou, Eduard,Juskova, Maria,Koukoulitsa, Cathrine,Nicolaou, Ioannis,Stefek, Milan,Demopoulos, Vassilis J.
, p. 1426 - 1433 (2011/04/15)
Based on our previous work, we studied the effect of methoxy-substitution as well as the regioposition of the benzoyl-moiety of 4a [(1-(3,5-difluoro-4- hydroxyphenyl)-1H-pyrrol-3-yl)(phenyl)methanone]. On this basis, compounds 4b-c and 5a-c were synthesiz