1273299-15-2Relevant academic research and scientific papers
Alkene isomerization/enamide-ene and diene metathesis for the construction of indoles, quinolines, benzofurans and chromenes with a chiral cyclopropane substituent
Kobayashi, Takaaki,Arisawa, Mitsuhiro,Shuto, Satoshi
, p. 1219 - 1224 (2011/04/15)
A synthetic method for bicyclic heterocycles, such as indole, benzofuran and chromene derivatives bearing a chiral cyclopropane at the 2-position, was established using isomerization of a terminal olefin and enamide-ene or diene metathesis. This route can also be applied to chiral 2-cyclopropylquinoline synthesis (both cis and trans).
