3867-18-3

Usage

Uses

Used in Pharmaceutical Industry:
2-Aminostyrene is used as a key intermediate in the synthesis of cyclopeptides, such as solomonamides, which are considered potential antitumor agents. These cyclopeptides have shown promising results in inhibiting the growth of cancer cells and are being investigated for their potential use in cancer treatment.
Used in Chemical Synthesis:
2-Aminostyrene serves as a valuable building block in the synthesis of various organic molecules, including pharmaceuticals, dyes, and other specialty chemicals. Its unique structure allows for a wide range of chemical reactions, making it a useful compound in the development of new materials and products.

Upstream product

• 579-71-5 2-nitrostyrene 
• 98-82-8 Isopropylbenzene 
• 102968-90-1 2-ethylthio-N-allylaniline 
• 917-54-4 methyllithium 
• 529-23-7 o-aminobenzaldehyde 
• 143879-49-6 2,2,2-trifluoro-N-(2-vinylphenyl)acetamide 
• 62-53-3 aniline 
• 74-86-2 acetylene 
• 5339-85-5 2-aminophenethyl alcohol 
• 2039-88-5 2-bromostyrene 
• 615-36-1 2-bromoaniline 
• 4627-10-5 4,4,6-trimethyl-2-vinyl-1,3,2-dioxaborinane 
• 29124-68-3 N-(2-vinylphenyl)acetamide 
• 88-72-2 1-methyl-2-nitrobenzene 

Downstream Products

• 860738-57-4 N,N'-bis-(2-vinyl-phenyl)-adipamide 
• 99058-19-2 chloro-acetic acid-(2-vinyl-anilide) 
• 123148-71-0 (2-Methoxy-pyridin-4-yl)-(2-vinyl-phenylamino)-acetic acid methyl ester 
• 94491-44-8 2-[2-(1-(4-Methoxy-benzenesulfonyl)-2-{[(E)-2-vinyl-phenylimino]-methyl}-1H-indol-3-yl)-ethyl]-isoindole-1,3-dione 
• 175846-71-6 N-(2-vinyl-phenyl)benzamide 
• 29124-68-3 N-(2-vinylphenyl)acetamide 
• 138386-53-5 C₂₆H₂₂NP 
• 1504-06-9 3-methylindolin-2-one 
• 553-03-7 3,4-dihydro-2(1H)-quinolone 
• 95-20-5 2-methyl-1H-indole 
• 91-63-4 2-methylquinoline 
• 1780-19-4 1,2,3,4-tetrahydro-2-methylquinoline 
• 612-62-4 2-Chloroquinoline 
• 632326-64-8 pent-4-enoic acid (2-vinylphenyl)amide 

Relevant academic research and scientific papers

BN Polystyrenes: Emerging Optical Materials and Versatile Intermediates

BN polystyrenes are an emerging class of polyolefins functionalized with aromatic side chains in which at least one CC bond is replaced with a BN bond. This class of structures exhibits unusual photophysical properties relative to organic polymers. BN pol

Precise molecular design for BN-modified polycyclic aromatic hydrocarbons toward mechanochromic materials

The development of smart materials, in particular those exhibiting highly sensitive mechanochromic luminescence (MCL) is desirable, but challenging since the MCL internal mechanism and the structure-performance relationship still remain unclear. Herein, w

Synthesis of triphenylarsonium [11C]methylide, a new 11C-precursor. Application in the preparation of [2-11C]indole

The synthesis of the new and highly reactive 11C-precursor triphenylarsonium [11C]methylide 1 and its conversion into [2-11C]indole 6 is described. [11C]Methyltriphenylarsonium iodide 4 was prepared by quaterniz

Ni-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Olefins by Intercepting Heck Intermediates as Imine-Stabilized Transient Metallacycles

We disclose a strategy for Ni-catalyzed dicarbofunctionalization of olefins in styrenes by intercepting Heck C(sp3)-NiX intermediates with arylzinc reagents. This approach utilizes a readily removable imine as a coordinating group that plays a

METHOD OF REDUCING AROMATIC NITRO COMPOUNDS

A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.

In-situ facile synthesis novel N-doped thin graphene layer encapsulated Pd@N/C catalyst for semi-hydrogenation of alkynes

Transition metal-catalyzed semi-hydrogenation of alkynes has become one of the most popular methods for alkene synthesis. Specifically, the noble metal Pd, Rh, and Ru-based heterogeneous catalysts have been widely studied and utilized in both academia and industry. But the supported noble metal catalysts are generally suffering from leaching or aggregation during harsh reaction conditions, which resulting low catalytic reactivity and stability. Herein, we reported the facile synthesis of nitrogen doped graphene encapsulated Pd catalyst and its application in the chemo-selective semi-hydrogenation of alkynes. The graphene layer served as “bulletproof” over the active Pd Nano metal species, which was confirmed by X-ray and TEM analysis, enhanced the catalytic stability during the reaction conditions. The optimized prepared Pd@N/C catalyst showed excellent efficiency in semi-hydrogenation of phenylacetylene and other types of alkynes with un-functionalized or functionalized substituents, including the hydrogenation sensitive functional groups (NO2, ester, and halogen).

DMSO/SOCl2-mediated C(sp2)-H amination: Switchable synthesis of 3-unsubstituted indole and 3-methylthioindole derivatives

The reaction of 2-alkenylanilines with SOCl2 in DMSO was found to selectively afford 3-unsubstituted indoles and 3-methylthioindoles. This switchable approach was found to be temperature-dependent: at room temperature, the reaction afforded 3-unsubstituted indoles through intramolecular cyclization and elimination; while at higher temperature, the reaction gave 3-methylthioindoles via further electrophilic methylthiolation.

Directing-group-assisted markovnikov-selective hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis

In contrast with the well-developed radical thiol-ene reaction to access anti-Markovnikov-type products, the research on the catalytic Markovnikov-selective hydrothiolation of alkenes is very restricted. Because of the catalyst poisoning of metal catalysts by organosulfur compounds, limited examples of transition-metal-catalyzed thiol-ene reactions have been reported. However, in this work, a directing-group-assisted hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis is found to proceed smoothly to afford Markovnikov-type sulfides with excellent regioselectivity.

Electrochemical-mediated fixation of CO2: three-component synthesis of carbamate compounds from CO2, amines andN-alkenylsulfonamides

An electrocatalyzed three-component cascade reaction of CO2, amines, andN-alkenylsulfonamides is developed, providing an environmentally friendly and efficient method of synthesizing a series of new carbamate compounds. This reaction meets the needs of green chemistry and promotes the participation of carbon dioxide in the three-component reaction by electro-oxidation. Pharmacological activity studies further prove that carbamate compounds have better activity than diamination by-products.

Uncovering New Excited State Photochemical Reactivity by Altering the Course of the de Mayo Reaction

An unprecedented and previously unknown photochemical reactivity of 1,3-dicarbonyl compounds is observed with amino-alkenes leading to dihydropyrans. This novel photochemical reactivity changes the established paradigm related to the De Mayo reaction between 1,3-dicarbonyl compounds and alkenes. This new reaction allows convenient access to the Marmycin core in a single step from commercially available reactants. The origin and scope of this new photoreaction is detailed with preliminary photophysical and mechanistic investigations.