1273326-28-5Relevant articles and documents
Enantioselective Friedel-Crafts alkylation of thiophenes with ethyl glyoxylate: Easy access to chiral secondary alcohols
Huang, Zhong,Zhang, Jingchang,Zhou, Yuqiang,Wang, Nai-Xing
supporting information; experimental part, p. 843 - 847 (2011/04/22)
Friedel-Crafts alkylation reactions of ethyl glyoxylate with various thiophenes to give the corresponding chiral secondary alcohols were demonstrated. The majority of these reactions proceeded with good enantioselectivities (up to 91%) and satisfactory is