1273564-99-0 Usage
General Description
3,3-difluorocyclobutanone is a chemical compound with the molecular formula C4H4F2O. It is a cyclobutanone derivative that contains two fluorine atoms attached to the carbon atoms at the 3-position of the cyclobutanone ring. 3,3-difluorocyclobutanone is primarily used as a synthetic intermediate in the production of various pharmaceuticals and agrochemicals. It is also used in organic synthesis to introduce fluorine atoms into organic molecules, which can enhance their biological activity or improve their chemical properties. 3,3-difluorocyclobutanone is a highly reactive compound that requires careful handling and specialized equipment for its synthesis and use in chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1273564-99-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,3,5,6 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1273564-99:
(9*1)+(8*2)+(7*7)+(6*3)+(5*5)+(4*6)+(3*4)+(2*9)+(1*9)=180
180 % 10 = 0
So 1273564-99-0 is a valid CAS Registry Number.
1273564-99-0Relevant articles and documents
Multigram Synthesis of C 4/C5 3,3-Difluorocyclobutyl-Substituted Building Blocks
Melnykov, Kostiantyn P.,Granat, Dmitriy S.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.,Grygorenko, Oleksandr O.
, p. 4949 - 4957 (2018)
An approach for the multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks (including carboxylic acid, amines, alcohols, azide, trifluoroborate ketone) is described. It is shown that, in most cases, ethyl 3,3-difluorocyclobutanecarboxylate is a convenient common synthetic intermediate to obtain the target derivatives. For preparation of 3,3-difluorocyclobutanol or -cyclobutanone, an alternative pathway via reaction of dichloroketene and tert -butyl or benzyl vinyl ether should be applied.
