127357-85-1

Basic information

• Product Name: (S)-cyanomethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate
• Synonyms: (S)-cyanomethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate
• CAS NO: 127357-85-1
• Molecular Weight: 304.346
• Mol File: 127357-85-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-cyanomethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-cyanomethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate(127357-85-1)
• EPA Substance Registry System: (S)-cyanomethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate(127357-85-1)

Safety Data

• Hazardous Substances Data: 127357-85-1(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 1333389-26-6 PheLysAlaAcm 
• 5956-81-0 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl 2-amino-3-phenylpropanoate 
• 1333389-11-9 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate 

Relevant articles and documents

Methods of modifying N-termini of a peptide or protein using transferases

The invention includes a selective method of modifying the N-terminus of a protein using an aminoacyl tRNA transferase. In certain embodiments, the method comprises contacting a solution of the protein or peptide with a transferase and a derivative of a molecule, whereby the N-terminus of the protein or peptide is derivatized with the molecule.

Enzymes as synthetic catalysts: Mechanistic and active-site considerations of natural and modified chymotrypsin

This paper describes the mechanistic investigation of α-chymotrypsin and [Met192-sulfoxide]-α-chymotrypsin-catalyzed peptide synthesis in a kinetically controlled process (i.e., aminolysis) and the relative stabilities of both enzymes in differ