1273587-36-2Relevant articles and documents
Pd-catalyzed α-arylation of nitriles and esters and γ-arylation of unsaturated nitriles with TMPZnCl?LiCl
Duez, Stephanie,Bernhardt, Sebastian,Heppekausen, Johannes,Fleming, Fraser F.,Knochel, Paul
supporting information; experimental part, p. 1690 - 1693 (2011/05/06)
Using TMPZnCl?LiCl as a kinetically highly active base, nitriles and esters undergo a Pd-catalyzed α-arylation under mild conditions. Remarkably, in the case of α,β- or β,γ-unsaturated nitriles, a regioselective γ-arylation or a γ-alkenylation is observed.