127382-97-2

Basic information

• Product Name: methyl N-(benzyloxycarbonyl)-α-bromoglycinate
• Synonyms: methyl N-(benzyloxycarbonyl)-α-bromoglycinate
• CAS NO: 127382-97-2
• Molecular Weight: 302.125
• Mol File: 127382-97-2.mol

Chemical Properties

• CAS DataBase Reference: methyl N-(benzyloxycarbonyl)-α-bromoglycinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-(benzyloxycarbonyl)-α-bromoglycinate(127382-97-2)
• EPA Substance Registry System: methyl N-(benzyloxycarbonyl)-α-bromoglycinate(127382-97-2)

Safety Data

• Hazardous Substances Data: 127382-97-2(Hazardous Substances Data)

Upstream product

• 127357-37-3 methyl 2-(benzyloxycarbonylamino)-2-methoxyacetate 
• 621-84-1 O-benzyl carbamate 
• 79002-45-2 N-benzyloxycarbonyl-glycine 
• 127357-38-4 N-(benzyloxycarbonyl)-α-hydroxy-glycine methyl ester 

Downstream Products

• 119839-48-4 methyl 2-amino-N-(benzyloxycarbonyl)-3-heptynoate 
• 119839-51-9 methyl 2-amino-N-(benzyloxycarbonyl)-4-phenyl-3-butynoate 
• 87376-42-9 [(E)-Benzyloxycarbonylimino]-acetic acid methyl ester 
• 914455-39-3 tert-butyl 2,2',2-(10-(1-(benzyloxycarbonylamino)-2-methoxy-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate 
• 127357-69-1 methyl 2-amino-N-(benzyloxycarbonyl)-3-butynoate 
• 127357-39-5 methyl 2-amino-N-(benzyloxycarbonyl)-4-(trimethylsilyl)-3-butynoate 
• 119839-50-8 methyl 2-amino-N-(benzyloxycarbonyl)-3-pentynoate 

Relevant articles and documents

Flexibly labeling peptides

A solid phase peptide synthesis method for synthesizing a peptidyl contrast agent is disclosed. In one example, the method includes synthesizing an amino-chelator loaded resin, coupling of the amino-chelator loaded resin to the C-terminus and/or backbone

A facile synthesis of α-amino-DOTA as a versatile molecular imaging probe

An amino group has been introduced into one ligand of DOTA that can couple to peptidyl carboxylates by coupling α-brominated glycine to DO3A-tBu (1,4,7,10-tetraazacyclododecane-1,4,7-tris(acetic acid, tert-butylester)). α-Amino-DOTA was coupled

Azabicycloalkenes as synthetic intermediates: Application to the preparation of diazabicycloalkane scaffolds

A general method to synthesize bicyclic dipeptide mimetics is reported. Key intermediates are azabicycloalkenes 9 and 17, which are prepared via Diels-Alder reactions and subsequent mild deprotection. These unsaturated bicyclic heterocycles are versatile

CONVERSION OF SERINE AND THREONINE RESIDUES INTO α-ACYLOXY-, α-ALKYLTHIO-, AND α-HALOGENOGLYCINE MOIETIES: A NEW STRATEGY FOR THE MODIFICATION OF PEPTIDES

Selective modification of serine and threonine containing peptides is accomplished by oxidation with lead tetraacetate.Conversion of the derived α-acetoxyglycine derivative into α-alkylthio- and α-halogenoglycine residues offers a novel synthetic route to

General Synthesis of β,γ-Alkynylglycine Derivatives

The coupling of α-haloglycinates 8 with alkynyltin reagents produces the fully protected β,γ-alkynylglycines 9.Subsequent deprotection of the amino or carboxyl groups generates differentially protected β,γ-alkynylglycine derivatives 10-14.The free amino a