127451-97-2Relevant academic research and scientific papers
Synthesis and biological properties of 4-substituted quinolin-2(1H)-one analogues
Jung, Jae-Chul,Oh, Seikwan,Kim, Won-Ki,Park, Woo-Kyu,Kong, Jae Yang,Park, Oee-Sook
, p. 617 - 623 (2007/10/03)
A variety of 4-substituted quinolin-2(1H)-ones were prepared and evaluated for N-methyl-D-aspartate (NMDA) receptor binding site activity and their abilities to inhibit neurotoxicity. The 4-(2-carbethoxyethanamino)- 7-chloro-3-nitroquinolin-2(1H)-one (9b)
Synthesis of 4-Hydroxyquinolin-2(1H)-one analogues and 2-substituted quinolone derivatives
Jung,Jung,Park
, p. 61 - 67 (2007/10/03)
A versatile synthetic method for preparing 4-hydroxyquinolone and 2-substituted quinolone compounds from simple benzoic acid derivatives was demonstrated. The synthetic strategies involve the use of well known ethyl acetoacetate synthesis, malonic ester s
