1274666-41-9Relevant academic research and scientific papers
Discovery of AMG 853, a CRTH2 and DP dual antagonist
Liu, Jiwen,Li, An-Rong,Wang, Yingcai,Johnson, Mike G.,Su, Yongli,Shen, Wang,Wang, Xuemei,Lively, Sarah,Brown, Matthew,Lai, Sujen,Gonzalez Lopez De Turiso, Felix,Xu, Qingge,Van Lengerich, Bettina,Schmitt, Mike,Fu, Zice,Sun, Ying,Lawlis, Shanna,Seitz, Lisa,Danao, Jay,Wait, Jill,Ye, Qiuping,Tang, Hua Lucy,Grillo, Mark,Collins, Tassie L.,Sullivan, Timothy J.,Medina, Julio C.
, p. 326 - 330 (2011/07/09)
Prostaglandin D2 (PGD2) plays a key role in mediating allergic reactions seen in asthma, allergic rhinitis, and atopic dermatitis. PGD2 exerts its activity through two G protein-coupled receptors (GPCRs), prostanoid D rece
