127479-75-8Relevant academic research and scientific papers
Synthesis and anticancer activity of 3′-[4-fluoroaryl-(1,2,3-triazol-1-yl)]-3′-deoxythymidine analogs and their phosphoramidates
Kleczewska, Natalia,Ruszkowski, Piotr,Singh, Aleksandra,Trznadel, Roksana,Celewicz, Lech
, p. 605 - 641 (2019/04/17)
A series of novel 4-chlorophenyl N-alkyl phosphoramidates of 3′-[4-fluoroaryl-(1,2,3-triazol-1-yl)]-3′-deoxythymidines (20–49) was synthesized by means of phosphorylation of 3′-[4-aryl-(1,2,3-triazol-1-yl)]-3′-deoxythymidines (7–11) with 4-chlorophenyl ph
3′-(1,2,3-Triazol-1-yl)-3′-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations
Lin, Jay,Roy, Vincent,Wang, Liya,You, Li,Agrofoglio, Luigi A.,Deville-Bonne, Dominique,McBrayer, Tamara R.,Coats, Steven J.,Schinazi, Raymond F.,Eriksson, Staffan
experimental part, p. 3261 - 3269 (2010/07/08)
The pathogenic mycoplasma Ureaplasma parvum (Up) causes opportunistic infections and relies on salvage of nucleosides for DNA synthesis and Up thymidine kinase (UpTK) provides the necessary thymidine nucleotides. The anti-HIV compound 3?-azido-3′-deoxythy
