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New Heterocyclic Structures. Thiazinopurine and Triazolothiazinopyrimidine
Pecorari, Piergiorgio,Rinaldi, Marcella,Costi, Maria Paola
, p. 1701 - 1705 (2007/10/02)
Derivatives of two new molecular structures, namely, thiazinopurine and triazolothiazinopyrimidine, were synthesized together with other heterocyclic compounds.Retrosynthetic analysis of their molecular skeletons suggested a simple way of obtaining 3,4-dihydro-7,8-diamino-2H,6H-pyrimidothiazin-6-one, which is a useful intermediate for their synthesis.This intermediate and the thiazole homologue were obtained directly by reaction of 5,6-diamino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone with 1,3- or 1,2-dibromoalkane, respectively.
