1275595-33-9

Basic information

• Product Name: MAGNOLIN
• Synonyms: rel-(7S7'S8R8'R)-Magnolin;1H,3H-Furo[3,4-c]furan, 1-(3,4-dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-, (1R,3aS,4R,6aS)-rel-
• CAS NO: 1275595-33-9
• Molecular Formula: C23H28O7
• Molecular Weight: 416.46
• Mol File: 1275595-33-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: MAGNOLIN(CAS DataBase Reference)
• NIST Chemistry Reference: MAGNOLIN(1275595-33-9)
• EPA Substance Registry System: MAGNOLIN(1275595-33-9)

Safety Data

• Hazardous Substances Data: 1275595-33-9(Hazardous Substances Data)

Usage

General Description

Magnolin is a chemical compound found in the bark and flower buds of the magnolia tree that has been shown to have potential health benefits. It is a natural polyphenol that exhibits anti-inflammatory, antioxidant, and anticancer properties. Magnolin has been studied for its ability to inhibit the growth of cancer cells and reduce inflammation in the body. It is also being investigated for its potential use in treating a range of health conditions, including neurodegenerative diseases, cardiovascular diseases, and skin disorders. Additionally, magnolin has been found to possess significant antioxidant activity, which helps protect cells from damage caused by free radicals. Overall, magnolin shows promise as a therapeutic agent with various potential health benefits.

Upstream product

• 100619-47-4 N,N-dimethyl-2-(3,4,5-trimethoxyphenyl)acetamide 
• 39053-78-6 3,4,5-trimethoxyphenylacetyl chloride 
• 951-82-6 3,4,5-trimethoxyphenyl acetic acid 
• 124-63-0 methanesulfonyl chloride 
• 186581-53-3 diazomethane 

Relevant articles and documents

A LIGNAN FROM LINDERA PRAECOX

A new 2,6-diaryl-3,7-dioxabicyclooctane lignan, praderin, was isolated from the leaves of Lindera praecox.Key Word Index-Lindera praecox; Lauraceae; lignan; praderin; isomagnolin; philligenin.

C-H insertion approach to the synthesis of endo,exo-furofuranones: Synthesis of (±)-asarinin, (±)-epimagnolin A, and (±)-fargesin

A series of novel 5-aryl-4-aryloxymethyl-3-diazotetrahydrofuran-2-ones (12, 24, and 35a/b) have been prepared and found to undergo regio- and stereoselective C-H insertion reactions to afford 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane-8-ones (18, 26, and 36a/b) with endo,exo stereochemistry. Subsequent reduction of the lactone ring and cyclization of the resulting diols 27 and 37a/b permitted the synthesis of three endo, exo-furofuran lignans: asarinin (2), fargesin (3), and epimagnolin A (4). En route to the key diazo compounds 24 and 35a/b, a modified procedure for the Ghosez keteniminium-olefin cyclization was developed, which was required to minimize the decomposition of acid-sensitive functional groups such as electron-rich benzylic ethers that were present in the target compounds 2-4.