127588-70-9

Upstream product

• 40653-15-4 methyl 2,3,4-tri-O-benzyl-α-D-manno-hexodialdo-1,5-pyranoside 
• 18171-11-4 chloromethylisopropoxydimethylsilane 
• 122588-50-5 (dimethylisopropoxysilyl)methylmagnesium chloride 

Downstream Products

• 131289-53-7 methyl 2,4-di-O-acetyl-6-O-benzoyl-7-O-(tert-butyldimethylsilyl)-3-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-L-glycero-α-D-manno-heptopyranoside 
• 131289-47-9 methyl 6-O-benzoyl-2,3,4-tri-O-benzyl-7-O-(2,3,4,6,7-penta-O-acetyl-L-glycero-α-D-manno-heptopyranosyl)-L-glycero-α-D-manno-heptopyranoside 
• 131289-49-1 methyl 2,4-di-O-acetyl-6-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-glycero-α-D-manno-heptopyranoside 
• 131289-43-5 methyl 6-O-benzoyl-2,3,4-tri-O-benzyl-7-O-(tert-butyldimethylsilyl)-L-glycero-α-D-manno-heptopyranoside 
• 131289-46-8 methyl 6-O-benzoyl-2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranoside 
• 155020-84-1 methyl 2,3,4-tri-O-benzyl-7-O-tert-butyldimethylsilyl-L-glycero-α-D-manno-heptopyranoside 
• 131289-44-6 methyl 6-O-benzoyl-7-O-(tert-butyldimethylsilyl)-L-glycero-α-D-manno-heptopyranoside 
• 131316-89-7 methyl 2,4-di-O-acetyl-6-O-benzoyl-7-O-(2,3,4,6,7-penta-O-acetyl-L-glycero-α-D-manno-heptopyranosyl)-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-L-glycero-α-D-manno-heptopyranoside 
• 127588-75-4 C₄₈H₅₀O₁₆ 
• 127642-33-5 methyl L-glycero-α-D-manno-heptopyranoside 
• 122588-51-6 methyl-2,3,4-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranoside 

Relevant academic research and scientific papers

Synthesis of methyl 3-O-(α-D-glucopyranosyl)-7-O-(L-glycero-α-D-manno-heptopyranosyl)-L-glycero-α-D-manno-heptopyranoside

The title trisaccharide glycoside, which is related to part of the core region of the lipopolysaccharide from Salmonella, and the disaccharide glycosides methyl 3-O-α-D-glucopyranosyl-L-glycero-α-D-manno-heptopyranoside and methyl 7-O-L-glycero-α-D-manno-heptopyranosyl-L-glycero-α-D-manno-heptopyranoside have been synthesised.Methyl 2,3,4-tri-O-benzyl-L-glycero-α-D-manno-heptopyranoside, obtained via a one-carbon elongation at C-6 of methyl 2,3,4-tri-O-benzyl-α-D-manno-hexodialdo-1,5-pyranoside, was used as precursor both for the heptosyl donor and acceptor.

Synthesis of L-glycero-α-D-manno-heptopyranose-containing disaccharide derivatives of the Neisseria meningitidis dephosphorylated inner-core region

Hydroxymethylation of correctly protected alkyl α-D-manno-hexodialdo-1,5-pyronosides with magnesium chloride affords the corresponding silane intermediated, the isopropoxydimethylsilyl group of which can be unmasked with h