127599-60-4Relevant academic research and scientific papers
N-(2,2,2-TRICHLOROETHYLIDENE)ARENESULFONAMIDES AND N-(2,2,2-TRICHLOROETHYLIDENE)ETHOXYFORMAMIDES IN REACTIONS WITH AMINES
Mirskova, A. N.,Levkovskaya, G. G.,Bryuzgin, A. A.,Drozdova, T. I.,Kalikhman, I. D.,Voronkov, M. G.
, p. 119 - 125 (2007/10/02)
The reaction of highly electrophilic N-(2,2,2-trichloroethylidene)arenesulfonamides with primary alkylamines and arylalkylamines leads to the formation of the addition products N-arenesulfonamides.These compounds are unstable, and this is due to the presence of the three electronegative substituents at the methine carbon atom.More basic dialkylamines lead to haloform decomposition of the N-(2,2,2-trichloroethylidene)arenesulfonamides and give high yields of dialkylarenesulfonylformamidines.At the same time dialkylamines add to N-(2,2,2-trichloroethylidene)etoxyformamide, forming N-ethoxyformamide.In reaction with trichloroethylideneethoxyformamide dimethylethanolamine forms the O-amidoalkylation product, i.e., N-ethoxyformamide, but its reaction with N-(2,2,2-trichloroethylidene)arenesulfonamide gives rise to its haloform decomposition with the formation of the corresponding arenesulfonamide.
