1276110-96-3Relevant academic research and scientific papers
Chiral Bronsted acid catalyzed enantioselective propargylation of aldehydes with allenylboronate
Reddy, Leleti Rajender
, p. 1142 - 1145 (2012)
A highly enantioselective chiral Bronsted acid catalyzed propargylation of aldehydes with allenylboronate is described. The reaction is shown to be practical and quite general with a broad substrate scope covering aryl, polyaryl, heteroaryl, α,β-unsaturat
A facile lipase-catalyzed KR approach toward enantiomerically enriched homopropargyl alcohols
Borowiecki, Pawe?,Dranka, Maciej
supporting information, (2019/02/14)
Compounds possessing propargylic (prop-2-ynylic) system are very important building blocks for organic chemistry. Among them, preparation of enantiomeric homopropargyl alcohols (but-3-yn-1-ols) constitutes a key-challenge for asymmetric synthesis and thus
Ligand-accelerated enantioselective propargylation of aldehydes via allenylzinc reagents
Trost, Barry M.,Ngai, Ming-Yu,Dong, Guangbin
supporting information; experimental part, p. 1900 - 1903 (2011/06/21)
An enantioselective propargylation of aldehydes using an allenylzinc reagent generated in situ via a zinc-iodine exchange reaction is described. The enantioselectivity is controlled by addition of a catalytic amount of readily accessible and highly tunable amino alcohol ligand L13. A wide range of aldehydes can be propargylated to afford valuable and versatile homopropargyl alcohols in good to excellent yields with high levels of enantiopurity.
Helical chiral 2,2′-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane
Chen, Jinshui,Captain, Burjor,Takenaka, Norito
supporting information; experimental part, p. 1654 - 1657 (2011/05/15)
A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2′-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylati
