1276110-97-4Relevant academic research and scientific papers
Optimization of Catalyst Structure for Asymmetric Propargylation of Aldehydes with Allenyltrichlorosilane
Vaganov, Vladimir Yu.,Fukazawa, Yasuaki,Kondratyev, Nikolay S.,Shipilovskikh, Sergei A.,Wheeler, Steven E.,Rubtsov, Aleksandr E.,Malkov, Andrei V.
supporting information, p. 5467 - 5474 (2020/10/19)
The design of catalysts for asymmetric propargylations remains a challenging task, with only a handful of methods providing access to enantioenriched homopropargylic alcohols. In this work, guided by previously reported computational predictions, a set of
A facile lipase-catalyzed KR approach toward enantiomerically enriched homopropargyl alcohols
Borowiecki, Pawe?,Dranka, Maciej
supporting information, (2019/02/14)
Compounds possessing propargylic (prop-2-ynylic) system are very important building blocks for organic chemistry. Among them, preparation of enantiomeric homopropargyl alcohols (but-3-yn-1-ols) constitutes a key-challenge for asymmetric synthesis and thus
Enantioselective Allyl-, and Allenylboration of Aldehydes Catalyzed by Chiral Hydroxyl Carboxylic Acid
Ota, Yuya,Kawato, Yuji,Egami, Hiromichi,Hamashima, Yoshitaka
supporting information, p. 976 - 980 (2017/05/05)
Asymmetric allylboration of aldehydes with allylboronic acid pinacol ester catalyzed by chiral hydroxyl carboxylic acid is described. This reaction provides synthetically useful homoallyl alcohols in high yield with good to high enantioselectivity. The pr
Helical chiral 2,2′-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane
Chen, Jinshui,Captain, Burjor,Takenaka, Norito
supporting information; experimental part, p. 1654 - 1657 (2011/05/15)
A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2′-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylati
