1276114-82-9

Basic information

• Product Name: 5-(cyclopent-1-en-1-yl)-2-(2-hydroxyethyl)-2-(phenylthio)pentanenitrile
• Synonyms: 5-(cyclopent-1-en-1-yl)-2-(2-hydroxyethyl)-2-(phenylthio)pentanenitrile
• CAS NO: 1276114-82-9
• Molecular Weight: 301.453
• Mol File: 1276114-82-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(cyclopent-1-en-1-yl)-2-(2-hydroxyethyl)-2-(phenylthio)pentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(cyclopent-1-en-1-yl)-2-(2-hydroxyethyl)-2-(phenylthio)pentanenitrile(1276114-82-9)
• EPA Substance Registry System: 5-(cyclopent-1-en-1-yl)-2-(2-hydroxyethyl)-2-(phenylthio)pentanenitrile(1276114-82-9)

Safety Data

• Hazardous Substances Data: 1276114-82-9(Hazardous Substances Data)

Upstream product

• 5219-61-4 (phenylthio)acetonitrile 
• 34714-03-9 1-bromo-2-[(trimethylsilyl)oxy]ethane 
• 1276114-81-8 5-(cyclopent-1-en-1-yl)-2-(phenylthio)pentanenitrile 

Downstream Products

• 1276114-83-0 2-(2-chloroethyl)-5-(cyclopent-1-en-1-yl)-2-(phenylthio)pentanenitrile 
• 1276114-84-1 2-(2-chloroethyl)-5-(cyclopent-1-en-1-yl)-2-(phenylthio)pentanal 

Relevant articles and documents

Synthesis of the core ring system of the yuzurimine-type daphniphyllum alkaloids by cascade condensation, cyclization, cycloaddition chemistry

Addition of hydroxylamine to substituted 4-chlorobutanals gives intermediate nitrones that undergo tandem cyclization and then intramolecular dipolar cycloaddition to give the core ring system of the yuzurimine-type natural products. Ring-opening of the isoxazolidines gives amino alcohols that can be converted to 1,3-oxazines, representing the tetracyclic core of alkaloids such as daphcalycic acid and daphcalycine.