1276122-01-0

Basic information

• Product Name: tert-butyl (3R,4S)-3-hydroxy-4-methylhex-5-enylcarbamate
• Synonyms: tert-butyl (3R,4S)-3-hydroxy-4-methylhex-5-enylcarbamate
• CAS NO: 1276122-01-0
• Molecular Weight: 229.32
• Mol File: 1276122-01-0.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl (3R,4S)-3-hydroxy-4-methylhex-5-enylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3R,4S)-3-hydroxy-4-methylhex-5-enylcarbamate(1276122-01-0)
• EPA Substance Registry System: tert-butyl (3R,4S)-3-hydroxy-4-methylhex-5-enylcarbamate(1276122-01-0)

Safety Data

• Hazardous Substances Data: 1276122-01-0(Hazardous Substances Data)

Upstream product

• 6737-11-7 2-acetoxy-3-butene 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 

Relevant articles and documents

Enhanced anti-diastereo- and enantioselectivity in alcohol-mediated carbonyl crotylation using an isolable single component iridium catalyst

The cyclometalated iridium complex (S)-I derived from [Ir(cod)Cl] 2, 4-cyano-3-nitrobenzoic acid, allyl acetate, and (S)-SEGPHOS is conveniently isolated by precipitation or through conventional silica gel flash chromatography. This single-component precatalyst allows alcohol mediated carbonyl crotylations to be performed at significantly lower temperature, resulting in enhanced levels of anti-diastereo- and enantioselectivity. Most significantly, the chromatographically isolated precatalyst (S)-I enables carbonyl crotylations that are not possible under previously reported conditions involving in situ generation of (S)-I.