127658-04-2Relevant academic research and scientific papers
(±)-Dioxolane-T ((±)-1-[(2β,4β)-2-(hydroxymethyl)-4-dioxolanyl]thymine). A new 2',3'-dideoxynucleoside prototype with in vitro activity against HIV
Norbeck,Spanton,Broder,Mitsuya
, p. 6263 - 6266 (2007/10/02)
A novel analogue of 3'-deoxythymidine, in which the 3'-carbon is replaced by oxygen, was synthesized in 5 steps from benzyloxyacetaldehyde dimethyl acetal and (±)-methyl glycerate. In ATH8 cells, this analogue showed significant inhibition of the infectiv
