127660-87-1Relevant academic research and scientific papers
Heterogeneous Ru/TiO2for hydroaminomethylation of olefins: multicomponent synthesis of amines
An, Jinghua,Gao, Zhuyan,Wang, Yehong,Zhang, Zhixin,Zhang, Jian,Li, Lu,Tang, Bo,Wang, Feng
supporting information, p. 2722 - 2728 (2021/04/21)
Synthesizing aminesviathe hydroaminomethylation (HAM) reaction of olefins, a multicomponent reaction, has been regarded as one of the most attractive methods compared with the traditional methods considering the atom economy and environmental friendliness. However, the use of homogeneous catalysts, complex ligands containing diphosphine or nitrogen, and base or acid additives has severely hampered the utilization of these methods. Herein, an efficient heterogeneous Ru/TiO2-catalyzed HAM reaction of olefins is developed without any additives. Various amines, including secondary and tertiary amines, can be successfully obtained from olefins including aromatic and aliphatic olefins. Systematic studies demonstrate the lower electron density of Ruδ+and the higher number of acid sites of Ru/TiO2, leading to the high HAM reaction activity of olefins. Most importantly, nitrobenzene derivatives can also be transformed to the corresponding products over Ru/TiO2in excellent yields.
Selective synthesis of N-(cyclohexylmethyl)-N-alkylamines from primary amines and pimelaldehyde using tetracarbonylhydridoferrate, HFe(CO)4-, as a reducing reagent
Shim,Kwon,Doh,Kim,Kim
, p. 105 - 106 (2007/10/02)
Treatment of primary amines with pimelaldehyde in the presence of tetracarbonyl-hydridoferrate, HFe(CO)4- at room temperature under atmospheric pressure of CO for 24 hours gave selectively corresponding N-(cyclohexylmethyl)-N-alkylam
