1277172-81-2

Upstream product

• 115586-67-9 (2R,3S)-3-O-benzyl-4-pentene-1,2,3-triol 
• 108275-52-1 (+)-(3S,4R)-3-benzyloxy-4,5-O-isopropylidene-4,5-dihydroxy-1-pentene 
• 100-39-0 benzyl bromide 
• 1277172-58-3 (2R,3S)-3-(benzyloxy)-1-(trityloxy)pent-4-en-2-ol 
• 1277172-78-7 benzyl (2S,3R,4R,5R)-3,4,5-tris(benzyloxy)-2-(hydroxymethyl)piperidine-1-carboxylate 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 1277172-76-5 benzyl (2S,3R,4R,5R)-3,4,5-tris(benzyloxy)-2-(trityloxymethyl)piperidine-1-carboxylate 
• 1277172-74-3 benzyl (2S,3R,4R,5R)-3-(benzyloxy)-4,5-dihydroxy-2-(trityloxymethyl)piperidine-1-carboxylate 
• 1277172-73-2 benzyl (2S,3S)-3-(benzyloxy)-2-(trityloxymethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate 
• 1277172-72-1 benzyl allyl[(2S,3S)-3-(benzyloxy)-1-(trityloxy)pent-4-en-2-yl]carbamate 
• 1277172-83-4 benzyl (2S,3S)-[3-(benzyloxy)-1-(trityloxy)pent-4-en-2-yl]carbamate 
• 1277172-60-7 (2S,3S)-2-azido-3-(benzyloxy)-1-(trityloxy)pent-4-ene 
• 1277172-59-4 (2R,3S)-3-(benzyloxy)-1-(trityloxy)pent-4-en-2-yl methanesulfonate 

Relevant academic research and scientific papers

Synthesis of aminocyclitols and trihydroxylated indolizidinone from a D-mannitol-derived common building block

The synthesis of 4-amino-4-deoxy-muco-quercitol (22), 4-amino-4-deoxy-(-)- vibo-quercitol (27) and also a trihydroxylated indolizidinone 38 from D-mannitol is described using ring-closing metathesis and diastereoselective dihydroxylation as the key steps.