127718-30-3

Upstream product

• 90-02-8 salicylaldehyde 
• 1689-05-0 4-phenyl-1-piperazineacetic acid hydrazide 
• 56968-26-4 ethyl 2-(4-phenyl-piperarazin-1-yl)acetate 
• 92-54-6 4-phenyl-1-piperazine 

Downstream Products

• 127718-37-0 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(2-chloro-phenylazo)-1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 127718-40-5 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(2-hydroxy-phenyl)-1-o-tolylazo-meth-(E)-ylidene]-hydrazide 
• 127718-43-8 2-(4-Chloro-phenyl)-5-(2-hydroxy-phenyl)-3-[2-(4-phenyl-piperazin-1-yl)-acetyl]-3H-tetrazol-2-ium; chloride 
• 127718-35-8 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(2-hydroxy-phenyl)-1-phenylazo-meth-(E)-ylidene]-hydrazide 
• 127718-39-2 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(4-chloro-phenylazo)-1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 127718-46-1 2-[5-(4-Phenyl-piperazin-1-ylmethyl)-[1,3,4]oxadiazol-2-yl]-phenol 
• 127718-36-9 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(2-chloro-4-nitro-phenylazo)-1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 127718-38-1 (4-Phenyl-piperazin-1-yl)-acetic acid [1-(3-chloro-phenylazo)-1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 

Relevant academic research and scientific papers

Piperazine clubbed with 2-azetidinone derivatives suppresses proliferation, migration and induces apoptosis in human cervical cancer HeLa cells through oxidative stress mediated intrinsic mitochondrial pathway

Abstract: Piperazine scaffolds or 2-azetidinone pharmacophores have been reported to show anti-cancer activities and apoptosis induction in different types of cancer cells. However, the mechanistic studies involve in induction of apoptosis addressing thes