1277187-96-8

Basic information

• Product Name: 1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 1277187-96-8
• Molecular Weight: 343.423
• Mol File: 1277187-96-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline(1277187-96-8)
• EPA Substance Registry System: 1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline(1277187-96-8)

Safety Data

• Hazardous Substances Data: 1277187-96-8(Hazardous Substances Data)

Upstream product

• 59756-83-1 2-(3-(benzyloxy)phenyl)acetyl chloride 
• 39053-78-6 3,4,5-trimethoxyphenylacetyl chloride 
• 4838-96-4 N-methyl-3,4,5-trimethoxyphenethylamine 
• 951-82-6 3,4,5-trimethoxyphenyl acetic acid 
• 1860-58-8 3-benzyloxyphenylacetic acid 
• 621-37-4 m-hydroxyphenylacetic acid 
• 1277187-95-7 1-(3-benzyloxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1277187-94-6 2-(3-benzyloxyphenyl)-N-methyl-N-(3,4,5-trimethoxyphenethyl)acetamide 

Downstream Products

• 1316259-15-0 (R)-1-(3-hydroxybenzyl)-2-methyl-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1316259-14-9 (S)-9-hydroxy-1,2,3-trimethoxyberbine 

Relevant articles and documents

Biocatalytic enantioselective oxidative C-C coupling by aerobic C-H activation

Bridging the gap: The berberine bridge enzyme (BBE) was employed for the first preparative oxidative biocatalytic C-C coupling that leads to a new intramolecular bond. This unique transformation requires O2 as sole stoichiometric oxidant and gives access to novel optically pure (S)-berbine 2 and (R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline 1 alkaloid derivatives by kinetic resolution.