127727-07-5

Basic information

• Product Name: 2-(4-nitrobenzamido)-3-phenylpropanoic acid
• Synonyms: 2-(4-nitrobenzamido)-3-phenylpropanoic acid
• CAS NO: 127727-07-5
• Molecular Weight: 314.298
• Mol File: 127727-07-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-nitrobenzamido)-3-phenylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrobenzamido)-3-phenylpropanoic acid(127727-07-5)
• EPA Substance Registry System: 2-(4-nitrobenzamido)-3-phenylpropanoic acid(127727-07-5)

Safety Data

• Hazardous Substances Data: 127727-07-5(Hazardous Substances Data)

Upstream product

• 150-30-1 Phenylalanine 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 1445980-06-2 C₃₀H₂₅N₃O₇S 
• 66421-85-0 2-(p-nitrophenyl)-4-benzyl-δ2-oxazolin-5-one 
• 101399-39-7 N-(4-amino-benzoyl)-phenylalanine 

Relevant articles and documents

Catalytic, Enantioselective α-Alkylation of Azlactones with Nonconjugated Alkenes by Directed Nucleopalladation

A palladium(II)-catalyzed enantioselective α-alkylation of azlactones with nonconjugated alkenes is described. The reaction employs a chiral BINOL-derived phosphoric acid as the source of stereoinduction, and a cleavable bidentate directing group appended to the alkene to control the regioselectivity and stabilize the nucleopalladated alkylpalladium(II) intermediate in the catalytic cycle. A wide range of azlactones were found to be compatible under the optimal reaction conditions to afford products bearing α,α-disubstituted α-amino-acid derivatives with high yields and high enantioselectivity.