127739-89-3 Usage
Chemical structure
A complex organic compound with a tetrazolium salt core.
Target
PAX3-FOXO1 fusion protein.
Role
Potent and highly selective inhibitor of the novel oncogene PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS).
Antitumor activity
Has shown promising antitumor activity in preclinical studies.
Therapeutic potential
May have potential therapeutic applications in the treatment of ARMS and other cancers with similar genetic aberrations.
Mechanism of action
Targeting the PAX3-FOXO1 fusion protein, which plays a critical role in the development and progression of ARMS.
Selectivity
Ability to selectively target the PAX3-FOXO1 oncogene, making it a potential candidate for further development as a targeted therapy.
Further research
Needed to fully understand the therapeutic potential and safety profile of TPPA in clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 127739-89-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,3 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 127739-89:
(8*1)+(7*2)+(6*7)+(5*7)+(4*3)+(3*9)+(2*8)+(1*9)=163
163 % 10 = 3
So 127739-89-3 is a valid CAS Registry Number.
