127745-39-5Relevant articles and documents
Synthesis of cyanopyrroles
Cheng, Lingjiang,Lightner, David A.
, p. 46 - 48 (1999)
Regioselective synthesis of α-cyanopyrroles (vs. α- alkoxycarbonylpyrroles) using oximinocyanoacetate esters in a Knorr-type reductive condensation with β-diketones can be directed by the presence of water. Thus, methyl oximinocyanoacetate was reacted with pentane-2,4-dione in hot acetic acid in the presence of zinc dust to give exclusively 3,5- dimethylpyrrole-2-carbonitrile when the acetic acid was wet; whereas, in glacial acetic acid only methyl 3,5-dimethylpyrrole-2-carboxylate was isolated (~40% yield).
Crystal structures of the "two" 4-aminofurazan-3-carboxylic acids
Willer, Rodney L.,Storey, Robson F.,Frisch, Mark,Deschamps, Jeffery R.
, p. 227 - 231 (2012)
The crystal structures of the two compounds reported to be 4-aminofurazan-3-carboxylic acid have been determined. The compound reported by Sheremetev et al. (J Heterocycl Chem 2005, 42, 519) is the actual 4-aminofurazan-3-carboxylic acid. The compound reported by Meyer (Org Prep Proced Int 2004, 36, 361) is the interesting complex formed from a molecule of the acid and a molecule of the potassium salt of the acid..
A Safer Synthesis of the Explosive Precursors 4-Aminofurazan-3-Carboxylic Acid and its Ethyl Ester Derivative
Johnson, Eric C.,Miller, Christopher W.,Orlicki, Joshua A.,Sabatini, Jesse J.,Sausa, Rosario C.
, p. 599 - 603 (2020)
A safe and efficient one-pot synthesis of 4-aminofurazan-3-carboxylic acid and its hydrogen chloride gas-free conversion to the ethyl ester derivative are described. Previous syntheses of these intermediates were plagued with mischaracterization issues, low yields, and/or dangerous exothermic profiles. The safe scale-up of these materials not only provides benefits to the energetic materials community but may also be of importance to the pharmaceutical and agrochemicals industries.
An efficient strontium-based combustion inhibitor of ammonium perchlorate with a 2D-MOF structure
Huang, Yao,Peng, Rufang,Jin, Bo
, p. 11068 - 11074 (2021/07/06)
In this study, a new strontium 2D-MOF, {[Sr(AFCA)2(H2O)2]·2H2O}n(AFCA = 4-aminofurazan-3-carboxylic acid), was successfully prepared by slow evaporation at room temperature. Its structure was characterized by X-ray single-crystal diffractometry. DTA as an efficient thermal analysis method was used in this study to have a better understanding of the thermal decomposition of ammonium perchlorate (AP). The Kissinger and the Ozawa-Doyle methods were also applied to determine the apparent activation energy (E) and the pre-exponential factor (A) of AP thermal decomposition. After the addition of {[Sr(AFCA)2(H2O)2]·2H2O}nin AP, there is an increase of 85.97 °C in the LTD stage of AP thermal decomposition and an insignificant decrease of 24.32 °C in the HTD stage. With the help of the TG-DSC-DTG method, we analyse the catalytic mechanism of AP in the LTD stage in detail. {[Sr(AFCA)2(H2O)2]·2H2O}ncan act as an efficient combustion inhibitor for AP thermal decomposition.
