127760-06-9Relevant articles and documents
Asymmetric Induction in Nitrone Cycloadditions: A Total Synthesis of Acivicin by Double Asymmetric Induction
Mzengeza, Shadreck,Whitney, Ralph Allen
, p. 4074 - 4081 (2007/10/02)
A total synthesis of acivicin, (αS,5S)-α-amino-3-chloro-4,5-dihydroisoxazole-5-acetic acid, has been achieved in 39percent overall yield from a derivative of (2S)-vinylglycine.The required diastereomer was obtained in an extremaly efficient manner = 19