127761-74-4Relevant academic research and scientific papers
Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters
Doherty,Ashe,Barker,Blacklock,Butcher,Chandler,Dahlgren,Davies,Dorn Jr.,Finke,Firestone,Hagmann,Halgren,Knight,Maycock,Navia,O'Grady,Pisano,Shah,et al.
, p. 2513 - 2521 (2007/10/02)
Time-dependent inhibitors of the enzyme human leukocyte elastase have been developed based on the cephem nucleus. A series of cephalosporin tert-butyl esters has been examined, and the activity of these compounds has been found to be very sensitive to C-7
