127767-22-0Relevant academic research and scientific papers
Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor
Marder, Mariel,Zinczuk, Juan,Colombo, Maria I.,Wasowski, Cristina,Viola, Haydee,Wolfman, Claudia,Medina, Jorge H.,Ruveda, Edmundo A.,Paladini, Alejandro C.
, p. 2003 - 2008 (2007/10/03)
A series of halogenated/nitrated flavone compounds were synthesized. Some of the products were found to be potent central benzodiazepine receptor (BDZ-R) ligands. The structure-activity relationships (SAR) analysis of the new synthetic compounds, together with that of others already described, indicates that substitutions at position 6 or 6 and 3' in the flavone nucleus are the only ones that give rise to high affinity BDZ-R ligands.
The Synthesis and Spectroscopic Properties of Flavones: Special Mass Spectral Characteristics of 3-Methylflavones
Letcher, Roy M.
, p. 2901 - 2929 (2007/10/02)
The synthesis of twenty one methyl-, methoxy-, nitro- and halogen-substituted 3-methylflavones is described, and their spectroscopic characteristics are reported.In contrast to the mass spectra of 3-unsubstituted flavones, the most abundant ion exhibited
