127767-40-2Relevant academic research and scientific papers
Dimethylsulfoxide-iodine catalysed deprotection of 2′- allyloxychalcones: Synthesis of flavones
Lokhande, Pradeep D.,Sakate, Sachin S.,Taksande, Kiran N.,Navghare, Beena
, p. 1573 - 1574 (2007/10/03)
A new one-pot method is described for the removal of O-allyl protecting groups under oxidative conditions at neutral pH. 2′-Allyloxychalcones undergo deprotection and subsequent oxidative cyclisation to give flavones. The general applicability of the reagent has been studied.
Manganese(III) acetate mediated oxidation of flavanones: A facile synthesis of flavones
Singh, Om V.,Muthukrishnan,Raj, Gopan
, p. 2723 - 2728 (2007/10/03)
Oxidation of flavanones (1a-o) with manganese(III) acetate by heating in acetic acid in presence of perchloric acid afforded exclusively flavones (2a-o) by dehydrogenation in almost quantitative yields. Copyright Taylor & Francis, Inc.
Use of nitroflavonoids for the treatment of anxiety
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, (2008/06/13)
PCT No. PCT/GB96/02523 Sec. 371 Date Jul. 8, 1998 Sec. 102(e) Date Jul. 8, 1998 PCT Filed Oct. 16, 1996 PCT Pub. No. WO97/14414 PCT Pub. Date Apr. 24, 1997Methods of treating anxiety with flavonoid compounds according to Formula (I) and dimers thereof, co
Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor
Marder, Mariel,Zinczuk, Juan,Colombo, Maria I.,Wasowski, Cristina,Viola, Haydee,Wolfman, Claudia,Medina, Jorge H.,Ruveda, Edmundo A.,Paladini, Alejandro C.
, p. 2003 - 2008 (2007/10/03)
A series of halogenated/nitrated flavone compounds were synthesized. Some of the products were found to be potent central benzodiazepine receptor (BDZ-R) ligands. The structure-activity relationships (SAR) analysis of the new synthetic compounds, together with that of others already described, indicates that substitutions at position 6 or 6 and 3' in the flavone nucleus are the only ones that give rise to high affinity BDZ-R ligands.
Oxidation of Flavanones using Thallium(III) Salts: A New Route for the Synthesis of Flavones and Isoflavones
Khanna, Mahavir S.,Singh, Om V.,Garg, Chandra P.,Kapoor, Ram P.
, p. 2565 - 2568 (2007/10/02)
When treated with thallium(III) acetate in acetic acid or acetonitrile, flavanones undergo facile dehydrogenation to afford flavones whereas, upon treatment with thallium(III) toluene-p-sulfonate or thallium(III) nitrate in propionitrile or acetonitrile, respectively, they undergo oxidative 2,3-aryl migration to give isoflavones in high yield.
The Synthesis and Spectroscopic Properties of Flavones: Special Mass Spectral Characteristics of 3-Methylflavones
Letcher, Roy M.
, p. 2901 - 2929 (2007/10/02)
The synthesis of twenty one methyl-, methoxy-, nitro- and halogen-substituted 3-methylflavones is described, and their spectroscopic characteristics are reported.In contrast to the mass spectra of 3-unsubstituted flavones, the most abundant ion exhibited
