127792-36-3Relevant articles and documents
Hepatic metabolism of diclofenac: Role of human CYP in the minor oxidative pathways
Bort, Roque,MacE, Katherine,Boobis, Alan,Gomez-Lechon, Maria-Jose.,Pfeifer, Andrea,Castell, Jose
, p. 787 - 796 (2007/10/03)
The aim of this study was to re-examine the human hepatic metabolism of diclofenac, with special focus on the generation of minor hydroxylated metabolites implicated in the idiosyncratic hepatotoxicity of the drug. Different experimental approaches were u