6480-66-6

Basic information

• Product Name: 2,6-DICHLORO-4-METHOXYANILINE
• Synonyms: 2,6-DICHLORO-4-METHOXYANILINE;2,6-Dichloro-4-methoxybenzenamine;2,6-Dichloro-p-anisidine
• CAS NO: 6480-66-6
• Molecular Formula: C₇H₇Cl₂NO
• Molecular Weight: 192.04258
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 6480-66-6.mol

Chemical Properties

• Melting Point: 71°C
• Boiling Point: 267℃
• Flash Point: 115℃
• Appearance: /
• Density: 1.375
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 1.31±0.10(Predicted)
• CAS DataBase Reference: 2,6-DICHLORO-4-METHOXYANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-4-METHOXYANILINE(6480-66-6)
• EPA Substance Registry System: 2,6-DICHLORO-4-METHOXYANILINE(6480-66-6)

Safety Data

• Hazardous Substances Data: 6480-66-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,6-Dichloro-4-methoxyaniline is used as a synthetic intermediate for the production of a wide range of chemical compounds. Its unique molecular structure, featuring two chlorine atoms at the 2nd and 6th positions and a methoxy group at the 4th position of the aniline backbone, allows it to participate in various chemical reactions, making it a versatile building block in the synthesis of pharmaceuticals, dyes, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-Dichloro-4-methoxyaniline is used as a key component in the development of new drugs. Its chemical properties enable it to be modified and functionalized to create molecules with specific biological activities, targeting various therapeutic areas such as cardiovascular, neurological, and oncological diseases.
Used in Dye Manufacturing:
2,6-Dichloro-4-methoxyaniline is also employed in the dye manufacturing industry as a starting material for the synthesis of various types of dyes. These dyes find applications in different sectors, including textiles, plastics, and printing inks, where they impart color and enhance the visual appeal of the final products.
Used in Chemical Research:
Due to its unique chemical structure, 2,6-Dichloro-4-methoxyaniline is a valuable compound for research purposes. It is used in academic and industrial laboratories to study various aspects of organic chemistry, such as reaction mechanisms, stereochemistry, and the development of new synthetic methods. This research contributes to the advancement of chemical science and the discovery of novel applications for this versatile compound.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 47, p. 2816, 2004 DOI: 10.1021/jm030891w

InChI:InChI=1S/C7H7Cl2NO/c1-11-4-2-5(8)7(10)6(9)3-4/h2-3H,10H2,1H3

Upstream product

• 637-62-7 p-benzoquinone oxime 
• 7647-01-0 hydrogenchloride 
• 28987-59-9 3-chloro-4-nitroanisole 
• 33719-74-3 3,5-dichloroanisole 
• 591-35-5 3,5-dichlorophenol 
• 77-78-1 dimethyl sulfate 
• 50590-08-4 3,5-dichloro-4-nitrophenol 
• 67-56-1 methanol 
• 100948-83-2 3,5-dichloro-4-nitroanisole 
• 74672-01-8 3,5-dichloro-2-nitroanisole 
• 26880-35-3 [1,4]benzoquinone-mono-(O-benzoyl oxime ) 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 64118-84-9 4'-hydroxydiclofenac 
• 698357-45-8 2-[2-(2',6'-dichloro-4'-hydroxyphenylamino)phenyl]-N,N-dimethylacetamide 
• 1428768-47-1 C₁₈H₁₉BrCl₂FN₃O₃ 
• 1428768-46-0 C₁₈H₁₉Cl₃FN₃O₃ 
• 1408250-55-4 C₁₆H₁₇Cl₃FN₃O₄ 
• 1408250-54-3 C₁₆H₁₈Cl₃N₃O₄ 
• 1173435-28-3 (R)-5-chloro-1-(1-cyclopropylpropyl)-3-(2,6-dichloro-4-methoxyphenylamino)pyrazin-2(1H)-one 
• 1173435-49-8 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(2,6-dichloro-4-methoxyphenylamino)pyrazin-2(1H)-one 
• 1092065-43-4 C₂₇H₂₈Cl₂N₄O₄ 
• 20951-31-9 1,3-Dichloro-2-methanesulfonyl-5-methoxy-benzene 
• 20945-61-3 3,5-Dichloro-4-methanesulfonyl-phenol 
• 41363-16-0 4,4'-Dihydroxy-2,6,2',6'-tetrachlordiphenyl 
• 67625-05-2 N,N-diethyl-glycine-(2,6-dichloro-4-methoxy-anilide) 
• 254762-25-9 2-chloro-N-(2,6-dichloro-4-methoxy[2H₅]phenyl)-N-phenylacetamide 

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