127794-13-2Relevant academic research and scientific papers
Manganese-catalyzed homogeneous hydrogenation of ketones and conjugate reduction of α,β-unsaturated carboxylic acid derivatives: A chemoselective, robust, and phosphine-free in situ-protocol
Topf, Christoph,Vielhaber, Thomas
, (2021)
We communicate a user-friendly and glove-box-free catalytic protocol for the manganese-catalyzed hydrogenation of ketones and conjugated C[dbnd]C[sbnd]bonds of esters and nitriles. The respective catalyst is readily assembled in situ from the privileged [Mn(CO)5Br] precursor and cheap 2-picolylamine. The catalytic transformations were performed in the presence of t-BuOK whereby the corresponding hydrogenation products were obtained in good to excellent yields. The described system offers a brisk and atom-efficient access to both secondary alcohols and saturated esters avoiding the use of oxygen-sensitive and expensive phosphine-based ligands.
Highly Selective Heterogeneous Palladium-Catalyzed Hydrogenations Using Triethoxysilane and Water
Tour, James M.,Cooper, Joel P.,Pendalwar, Shekhar L.
, p. 3452 - 3453 (2007/10/02)
Treatment of alkenes or alkynes at ambient temperature with triethoxysilane and 5 mol percent of palladium(II) acetate in a mixture of tetrahydrofuran and water affords the corresponding hydrogenated products.Excellent chemoselectivities and stereoselectivities can be abtained using this process.
