127841-16-1

Basic information

• Product Name: 2-(4-Chloro-phenyl)-5-phenyl-1H-indole
• Synonyms: 2-(4-Chloro-phenyl)-5-phenyl-1H-indole
• CAS NO: 127841-16-1
• Molecular Weight: 303.791
• Mol File: 127841-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Chloro-phenyl)-5-phenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyl)-5-phenyl-1H-indole(127841-16-1)
• EPA Substance Registry System: 2-(4-Chloro-phenyl)-5-phenyl-1H-indole(127841-16-1)

Safety Data

• Hazardous Substances Data: 127841-16-1(Hazardous Substances Data)

Upstream product

• 1126-46-1 Methyl 4-chlorobenzoate 
• 127841-19-4 N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide 

Relevant articles and documents

A new approach to the synthesis of 2-substituted indoles: Reaction of dimetallated ortho-trimethylsilylmethylanilides with esters

The reaction of 2-trimethylsilylmethylanilides and esters in basic medium provides a new general method for the synthesis of indoles. The advantages of this method are the mild reaction conditions (-10-0°C), the ready availability of the starting materials and the use of a non-nucleophilic base (lithium 2,2,6,6-tetramethylpiperidide) to promote cyclisation.