127841-19-4

Basic information

• Product Name: N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide
• Synonyms: N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide
• CAS NO: 127841-19-4
• Molecular Weight: 359.543
• Mol File: 127841-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide(127841-19-4)
• EPA Substance Registry System: N-(3-Trimethylsilanylmethyl-biphenyl-4-yl)-benzamide(127841-19-4)

Safety Data

• Hazardous Substances Data: 127841-19-4(Hazardous Substances Data)

Upstream product

• 117616-02-1 3-Trimethylsilanylmethyl-biphenyl-4-ylamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 93-58-3 benzoic acid methyl ester 
• 127841-16-1 2-(4-Chloro-phenyl)-5-phenyl-1H-indole 
• 127841-15-0 5-Phenyl-2-p-tolyl-1H-indole 

Relevant articles and documents

A new approach to the synthesis of 2-substituted indoles: Reaction of dimetallated ortho-trimethylsilylmethylanilides with esters

The reaction of 2-trimethylsilylmethylanilides and esters in basic medium provides a new general method for the synthesis of indoles. The advantages of this method are the mild reaction conditions (-10-0°C), the ready availability of the starting materials and the use of a non-nucleophilic base (lithium 2,2,6,6-tetramethylpiperidide) to promote cyclisation.