1278575-44-2

Upstream product

• 150367-10-5 1-nitro-1-heptene 
• 1278575-08-8 C₂₂H₂₈N₂O 
• 1278574-96-1 C₂₂H₂₆N₂O₃ 
• 1278575-16-8 C₂₈H₄₂N₂OSi 
• 100-52-7 benzaldehyde 
• 120-72-9 indole 

Relevant academic research and scientific papers

Easy access to fully functionalized chiral tetrahydro-β-carboline alkaloids

A four-step synthetic route to fully substituted chiral tetrahydro-β-carbolines (THBCs) is described. Starting from the (R,S,S)-Friedel-Crafts/Henry adduct obtained from three-component coupling of an indole, nitroalkene, and aldehyde catalyzed by imidazoline-aminophenol-CuOTf, the (1S,3S,4R)-THBCs were readily synthesized in a three-step operation including reduction of the nitro-functionality and Pictet-Spengler cyclization.