1278579-60-4

Basic information

• Product Name: 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole
• Synonyms: 1-Methyl-1H-pyrrole-2,4-diboronic acid, pinacol ester;1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole
• CAS NO: 1278579-60-4
• Molecular Formula: C17H29B2NO4
• Molecular Weight: 333.03846
• Mol File: 1278579-60-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole(1278579-60-4)
• EPA Substance Registry System: 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole(1278579-60-4)

Safety Data

• Hazardous Substances Data: 1278579-60-4(Hazardous Substances Data)

Usage

General Description

1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole is a complex chemical compound with a long and specific name. It is a pyrrole derivative that contains two boron-containing groups, making it useful in various synthetic and medicinal chemistry applications. The compound has potential applications in materials science and pharmaceuticals, where it can be used as a building block for the synthesis of more complex molecules. Its unique structure and functional groups make it a valuable tool for chemical research and development. 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole has potential for application in organic synthesis, medicinal chemistry, and material science due to its unique structure and properties.

Upstream product

• 96-54-8 N-Methylpyrrole 
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• 55718-76-8 2-chloro-1,3,2-benzodioxaborole 
• 1278579-86-4 2,4-di(1,3,2-benzodioxaborolan-2-yl)-1-methyl-pyrrole 

Relevant articles and documents

Isodesmic C-H Borylation: Perspectives and Proof of Concept of Transfer Borylation Catalysis

The potential advantages of using arylboronic esters as boron sources in C-H borylation are discussed. The concept is showcased using commercially available 2-mercaptopyridine as a metal-free catalyst for the transfer borylation of heteroarenes using arylboronates as borylation agents. The catalysis shows a unique functional group tolerance among C-H borylation reactions, tolerating notably terminal alkene and alkyne functional groups. The mechanistic investigation is also described.

Pinacol boronates by direct arene borylation with borenium cations

Borenium does it direct: A boron analogue of the Friedel-Crafts reaction uses inexpensive catecholatoborenium cations that are sufficiently electrophilic to borylate arenes by electrophilic aromatic substitution. The direct arene borylation proceeds with high regioselectivity for a range of anilines, N-heterocycles, and thiophenes. Subsequent one-pot transesterification provides the synthetically useful pinacol boronate esters (see scheme).