127871-76-5Relevant academic research and scientific papers
Diastereomeric α-Phenylseleno Alkyllithium Compounds, Generation and Reactions
Hoffmann, Reinhard W.,Bewersdorf, Martin
, p. 643 - 654 (2007/10/02)
The selenoacetals 4 having a chiral center in the β-position were subjected to selenium/lithium exchange by butyllithium in ether.The resulting α-phenylseleno alkyllithium compounds 5 undergo rapid epimerization at -78 deg C.Trapping of these organolithiu
Diastereoselective reactions of seleno-acetals
Hoffmann, Reinhard W.,Bewersdorf, Martin
, p. 67 - 70 (2007/10/02)
The diastereoselective refunctionalization of the seleno-acetals 1b into various seleno-ethers 3b is reported. The diastereomer ratio of the products 3b reflects the thermodynamic ratio of the intermediate α-phenylselenolithium compounds 7 at -78°C.
