1279093-67-2

Upstream product

• 1279093-65-0 C₂₀H₂₈F₃NO₂Si 
• 1279093-64-9 C₁₄H₁₄F₃NO₂ 
• 908071-52-3 6-(2’-aminophenyl)hex-5-yn-1-ol 
• 928-90-5 5-hexyl-1-ol 
• 1279093-66-1 C₁₉H₁₇FN₂O 
• 124-63-0 methanesulfonyl chloride 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1279096-32-0 C₁₉H₁₅FN₂ 

Relevant academic research and scientific papers

HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS

The invention relates to therapeutic compounds that bind to HSP90. The compounds disclosed herein bind HSP90 and alter the chaperoning capability of HSP90 proteins. The invention also relates to pharmaceutical compositions comprising these compounds, and methods of treating or preventing fungal infections.

HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE FN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES

The invention relates to therapeutic compounds that bind to HSP90. The compounds disclosed herein bind HSP90 and alter the chaperoning capability of HSP90 proteins. The invention also relates to pharmaceutical compositions comprising these compounds, and methods of treating diseases and disorders such as cancer, autoimmune disease and other diseases.