1279096-14-8

Basic information

• Product Name: C₂₄H₂₆FN₃O₂
• Synonyms: C₂₄H₂₆FN₃O₂
• CAS NO: 1279096-14-8
• Molecular Weight: 407.488
• Mol File: 1279096-14-8.mol

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₆FN₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₆FN₃O₂(1279096-14-8)
• EPA Substance Registry System: C₂₄H₂₆FN₃O₂(1279096-14-8)

Safety Data

• Hazardous Substances Data: 1279096-14-8(Hazardous Substances Data)

Upstream product

• 31579-37-0 2-(hydroxyimino)cyclopentanone 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 1073973-23-5 (S)-4-bromo-2-fluoro-6-((tetrahydrofuran-3-yl)amino)benzonitrile 
• 1279095-97-4 C₁₃H₁₇NO 
• 123843-67-4 4-bromo-2,6-difluorobenzonitrile 

Downstream Products

• 1279094-40-4 C₂₄H₂₈FN₃O₃ 

Relevant articles and documents

HSP90 MODULATING COMPOUNDS, COMPOSITIONS, METHODS AND USES

The invention relates to therapeutic compounds which bind to HSP90, said compounds containing a benzamide group bound to a tricyclic condensed ring system via the nitrogen atom of a pyrrole located in the center of the condensed system. The compounds disclosed herein bind HSP90 and alter the chaperoning capability of HSP90 proteins. Intermediate benzonitrile compounds which are precursors to the benzamide compounds are also disclosed. The invention also relates to pharmaceutical compositions comprising these compounds, and methods of treating diseases and disorders such as cancer, autoimmune diseases and other diseases.