1279115-53-5

Basic information

• Product Name: 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane
• Synonyms: 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane
• CAS NO: 1279115-53-5
• Molecular Weight: 329.973
• Mol File: 1279115-53-5.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane(1279115-53-5)
• EPA Substance Registry System: 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane(1279115-53-5)

Safety Data

• Hazardous Substances Data: 1279115-53-5(Hazardous Substances Data)

Usage

General Description

2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane is a chemical compound with the molecular formula C12H18BIO2. It contains a boron atom and an iodine atom, along with a phenyl ring and a dioxaborinane moiety. 2-(4-iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane is a boronic ester, which is commonly used as a building block in organic synthesis and medicinal chemistry. It has been utilized in the development of pharmaceuticals, agrochemicals, and materials science, due to its ability to form carbon-carbon and carbon-heteroatom bonds through palladium-catalyzed coupling reactions. This versatile chemical has applications in the production of drugs, pesticides, and functional materials.

Upstream product

• 107-41-5 2-methyl-2,4-pentanediol 
• 5122-99-6 4-iodophenylboronic acid 
• 61676-61-7 2-isopropoxy-4,4,6-trimethyl-[1,3,2] dioxaborinane 
• 624-38-4 para-diiodobenzene 

Downstream Products

• 35444-94-1 1-benzyl-4-iodobenzene 

Relevant articles and documents

Feedstocks to Pharmacophores: Cu-Catalyzed Oxidative Arylation of Inexpensive Alkylarenes Enabling Direct Access to Diarylalkanes

A Cu-catalyzed method has been identified for selective oxidative arylation of benzylic C-H bonds with arylboronic esters. The resulting 1,1-diarylalkanes are accessed directly from inexpensive alkylarenes containing primary and secondary benzylic C-H bonds, such as toluene or ethylbenzene. All catalyst components are commercially available at low cost, and the arylboronic esters are either commercially available or easily accessible from the commercially available boronic acids. The potential utility of these methods in medicinal chemistry applications is highlighted.

Noncryogenic preparation of functionalized arylboronic esters through a magnesium-iodine exchange with in situ quench

Various functionalized aryl boronic esters derived from hexylene glycol and pinacol were prepared in excellent yields according to a simple, safe procedure. The metal-halogen exchange reaction between iPrMgCl? LiCl and aryl iodides is performed