127945-65-7 Usage
Properties
Potential anticancer properties
Drug Class
Proteasome inhibitors
Mechanism of Action
Inhibits the proteasome, leading to accumulation of proteins in cancer cells and triggering cell death
Current Status
Under investigation in clinical trials for potential as a new treatment option for cancer patients
Check Digit Verification of cas no
The CAS Registry Mumber 127945-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,4 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 127945-65:
(8*1)+(7*2)+(6*7)+(5*9)+(4*4)+(3*5)+(2*6)+(1*5)=157
157 % 10 = 7
So 127945-65-7 is a valid CAS Registry Number.
127945-65-7Relevant academic research and scientific papers
Synthesis and Antivirial Activity of Some Acyclic and C-Acyclic Pyrrolopyrimidine Nucleoside Analogues
Bennett, Sharon M.,Nguyen-Ba, Nghe,Ogilvie, Kelvin K.
, p. 2162 - 2173 (2007/10/02)
A series of acyclic and C-acyclic 7-deazapurine nucleosides have been synthesized and tested for antivirial activity.Reaction of the sodium salt of 2-amino-3,4-bis(aminocarbonyl)-5-(methylthio)pyrrole (6) with an appropriate electrophile gave pyrrole nucl
