1279708-85-8

Upstream product

• 1279708-94-9 C₃₉H₇₂O₂Si₂ 
• 1246364-54-4 [(E)-[(3'R)-[(tert-butyldimethylsilyl)oxy]-4'-methylenecyclohexylidene]ethyl]diphenylphosphine oxide 
• 1246364-52-2 (E)-2-[(R)-3'-[(tert-butyldimethylsilyl)oxy]-4'-methylene-cyclohexylidene]ethanol 
• 1279708-92-7 [(R)-3'-[(tert-butyldimethylsilyl)oxy]-4'-methylene-cyclohexylidene] acetic acid methyl ester 
• 1279708-93-8 C₄₉H₇₆O₂Si₂ 
• 1246364-32-8 (E)-2-[(R)-3'-[(tert-butyldiphenylsilyl)oxy]-4'-methylene-cyclohexylidene]ethanol 
• 1279708-81-4 [(R)-3'-[(tert-butyldiphenylsilyl)oxy]-4'-methylene-cyclohexylidene]acetic acid methyl ester 
• 1246364-29-3 (R)-3-[(tert-butyldiphenylsilyl)oxy]-4-methylene-cyclohexanone 
• 1246364-28-2 (R)-7-[(tert-butyldiphenylsilyl)oxy]-8-methylene-1,4-dioxa-spiro[4.5]decane 
• 1246364-27-1 (R)-7-[(tert-butyldiphenylsilyl)oxy]-1,4-dioxa-spiro[4.5]decan-8-one 
• 851764-31-3 (R)-4-hydroxy-1,4-dioxa-spiro[4.5]decan-8-one 
• 213250-68-1 1-(1,5-dimethyl-5-triethylsilanyloxy-hexyl)-7a-methyl-octahydro-inden-4-one 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Relevant academic research and scientific papers

1-Desoxy-2-Methylene-19-Nor-Vitamin D Analogs and Their Uses

This invention discloses 1-desoxy-2-methylene-19-nor-vitamin D analogs, and specifically (20S)-25-hydroxy-1-desoxy-2-methylene-19-nor-vitamin D3 and pharmaceutical uses therefor. This compound exhibits relatively high binding activity and prono

1-Desoxy analog of 2MD: Synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3

During our ongoing structure-activity studies in the vitamin D area, we obtained (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D3 (5). This analog, designated 2MD, is characterized by a significantly enhanced calcemic activity and is currentl