127971-97-5

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-3-methoxy-2-nitrobenzoic acid is utilized as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of potential therapeutic agents.
Used in Medicinal Chemistry:
In medicinal chemistry, 6-Bromo-3-methoxy-2-nitrobenzoic acid serves as a valuable building block for the development of new drugs, including those with anti-cancer properties, due to its versatile functional groups that can be modified to enhance biological activity.
Used in Organic Synthesis:
6-Bromo-3-methoxy-2-nitrobenzoic acid is employed as a reactant in organic synthesis processes, where its bromine atom, nitro group, and methoxy group can participate in a range of chemical reactions to form diverse organic compounds.
Used in the Development of Anti-Cancer Drugs:
6-Bromo-3-methoxy-2-nitrobenzoic acid is used as a precursor in the development of anti-cancer drugs, leveraging its chemical properties to create molecules that can target and combat cancer cells effectively.
Used in Other Fields of Science:
Beyond its applications in the pharmaceutical industry, 6-Bromo-3-methoxy-2-nitrobenzoic acid also finds use in other scientific fields where its chemical and physical properties can be exploited for various experimental and analytical purposes.

Upstream product

• 4920-80-3 3-methoxy-2-nitrobenzoic acid 
• 5345-42-6 1-methoxy-3-methyl-2-nitro-benzene 

Downstream Products

• 127972-20-7 methyl 2'-(benzyloxy)-5'-ethyl-4-methoxy-3-nitrobiphenyl-2-carboxylate 
• 127971-98-6 methyl 6-bromo-3-methoxy-2-nitrobenzoate 
• 1219130-47-8 5-bromo-8-methoxyquinazoline 
• 67303-48-4 2-amino-6-bromo-3-methoxybenzoic acid 

Relevant academic research and scientific papers

Total Synthesis of Waltherione F, a Nonrutaceous 3-Methoxy-4-quinolone, Isolated from Waltheria indica L. F.

Waltherione F was totally synthesized in seven steps and 31% overall yield from 2-nitro-3-methylanisole without the use of protecting groups. Key steps in the sequence were a Suzuki-Miyaura coupling to attach the n-octyl chain and a microwave-promoted cyclization of an acetonyl anthranilate to give the heterocyclic core whose 3-OH was O-methylated.

COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING COMPOUNDS AND OF THEIR USE

Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also di

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Benzoxazole carboxamides for treating CINV and IBS-D

Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.

Structural Elucidation and Independent Synthesis of the Radical-Radical Coupling Products of 3-Hydroxyanthranilic acid with Tyrosine and Phenols

The autoxidation of 3-hydroxyanthranilic acid (3OHA) in the presence of tyrosine, p-cresol, or p-ethylphenol gives dibenzopyran-6-one products that arise from the coupling of the radical of 3OHA with that derived from the substituted phenol.As a proo