127980-46-5 Usage
Uses
2-Amino-5,6-dimethoxypyridine is used in the design of Spleen Tyrosine Kinase (Syk) inhibitors used in the treatment of autoimmune diseases such as asthma, rheumatoid arthitis and SLE.
Check Digit Verification of cas no
The CAS Registry Mumber 127980-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,8 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127980-46:
(8*1)+(7*2)+(6*7)+(5*9)+(4*8)+(3*0)+(2*4)+(1*6)=155
155 % 10 = 5
So 127980-46-5 is a valid CAS Registry Number.
127980-46-5Relevant articles and documents
PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION
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Page/Page column 56, (2008/06/13)
There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.