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127984-23-0

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127984-23-0 Usage

General Description

(2R,3R)-2-AMINO-3-HYDROXY-PENTANOIC ACID, also known as threonine, is an essential amino acid that plays a key role in human nutrition and health. It is a crucial building block for proteins and is involved in various metabolic and physiological processes within the body. Threonine is essential for the formation of tooth enamel, collagen, and elastin, as well as for maintaining proper immune function and supporting the nervous system. It also serves as a precursor for the synthesis of important compounds such as glycine and serine. Threonine can be obtained through the diet by consuming protein-rich foods such as meat, fish, dairy products, and seeds.

Check Digit Verification of cas no

The CAS Registry Mumber 127984-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,8 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127984-23:
(8*1)+(7*2)+(6*7)+(5*9)+(4*8)+(3*4)+(2*2)+(1*3)=160
160 % 10 = 0
So 127984-23-0 is a valid CAS Registry Number.

127984-23-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R)-2-amino-3-hydroxypentanoic acid

1.2 Other means of identification

Product number -
Other names (3R)-3-hydroxy-D-norvaline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127984-23-0 SDS

127984-23-0Relevant articles and documents

DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA)

-

Paragraph 0369; 0370, (2013/06/06)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

A practical stereoselective synthesis of both enantiomers of Threo- and Erythro-β-hydroxy norvaline from (S)-serine derivatives

Andrés, José M.,Elena, Noemí De,Pedrosa, Rafael

, p. 1523 - 1531 (2007/10/03)

The four enantiopure diastereoisomers of β-hydroxy norvaline have been prepared from L-serine in moderate chemical yield. The method is based on the diastereoselective addition of different organometallics to easily accessible serinal derivatives. (C) 2000 Elsevier Science Ltd.

Chiral 4,5-Disubstituted Oxazolidin-2-ones: Stereoselective Synthesis of β-Hydroxy-α-amino Acids

Giovanni, Maria Cristina Di,Misiti, Domenico,Zappia, Giovanni,Monache, Giuliano Delle

, p. 475 - 482 (2007/10/03)

The stereocontrolled synthesis of β-hydroxy-α-amino acids from O-benzyl D- and L-serine, by the use of 4,5-disubstituted oxazolidin-2-ones as chiral intermediates, is presented as a suitable alternative to the known procedures.The reported synthesis of both enantiomers of threo-3-hydroxyglutamic acid and (2S,3R)-3-hydroxyproline together with a flexible and stereodivergent preparation of threonine analogues is discussed as an example of the versatility of the present approach.

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