128017-18-5Relevant academic research and scientific papers
Regioselective Reductive Ring Cleavage of 3-Benzyltetrahydro-1,3-oxazines to 3-Dialkylaminopropanols and of 3-Benzyl-3-methyltetrahydro-1,3-oxazinium Iodides to Alkyl 3-Dialkylaminopropyl Ethers
Alberola, Angel,Alvarez, M. Angeles,Andres, Celia,Gonzalez, Alfonso,Pedrosa, Rafael
, p. 153 - 156 (2007/10/02)
3-Benzyltetrahydro-1,3-oxazines and their methiodides are ring-cleaved upon reduction with lithium aluminum hydride to give 3-dialkylaminopropanols or alkyl 3-dialkylaminopropyl ethers, respectively, in good yields.The reducing agent regioselectively clea
SOME OBSERVATIONS ON THE REGIOSELECTIVE RING OPENING OF TETRAHYDRO-1,3-OXAZINIUM METHIODIDES BY SODIUM BOROHYDRIDE IN ALCOHOLIC AND ETHERAL SOLVENTS
Alberola, Angel,Andres, Celia,Delgado, Manuel,Gonzalez, Alfonso,Pedrosa, Rafael
, p. 2079 - 2084 (2007/10/02)
2-Substituted N-benzyl-N-methyltetrahydro-1,3-oxazinium iodides react with sodium borohydride in anhydrous THF leading to a mixture of 3-alkoxypropylamines and their borane complexes.In the contrary, when anhydrous methanol or ethanol is used as solvent,
