1280210-85-6

Basic information

• Product Name: tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-6-oxopiperidin-3-yl]carbamate
• Synonyms: tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-6-oxopiperidin-3-yl]carbamate
• CAS NO: 1280210-85-6
• Molecular Weight: 326.343
• Mol File: 1280210-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-6-oxopiperidin-3-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-6-oxopiperidin-3-yl]carbamate(1280210-85-6)
• EPA Substance Registry System: tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-6-oxopiperidin-3-yl]carbamate(1280210-85-6)

Safety Data

• Hazardous Substances Data: 1280210-85-6(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1280210-82-3 (5S,6R)-6-(2,5-difluorophenyl)-5-nitropiperidin-2-one 
• 2646-90-4 2,5-difluorobenzaldehyde 

Downstream Products

• 1280210-99-2 tert-butyl {(2R,3S,5R)-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]-1-(1,3-oxazol-4-ylmethyl)piperidin-3-yl}carbamate 
• 1280208-74-3 (2S)-1-{(2R,3S,5R)-3-amino-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]piperidin-1-yl}propan-2-ol 
• 1280211-00-8 tert-butyl {(2R,3S,5R)-2-(2,5-difiuorophenyl)-1-[(2S)-2-hydroxypropyl]-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]piperidin-3-yl}carbamate 
• 1280208-75-4 (2S)-1-[(2R,3S,5R)-3-amino-2-(2,5-difiuorophenyl)-5-(2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)piperidin-1-yl]propan-2-ol 
• 1280211-05-3 tert-butyl [(2R,3S,5R)-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]-1-(2-oxopropyl)piperidin-3-yl]carbamate 
• 1280211-06-4 tert-butyl {(2R,3S,5R)-2-(2,5-difiuorophenyl)-1-(2,2-difluoropropyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]piperidin-3-yl}carbamate bis(trifluoroacetic acid salt) 
• 1280211-09-7 tert-butyl {(2R,3S,5R)-1-(2-amino-2-oxoethyl)-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]piperidin-3-yl}carbamate 
• 1280211-10-0 {(2R,3S,5R)-3-[(tert-butoxycarbonyl)amino]-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]piperidin-1-yl}acetic acid 
• 1280211-13-3 tert-butyl [(2R,3S,5R)-2-(2,5-difiuorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]-1-(trifluoroacetyl)piperidin-3-yl]carbamate 

Relevant articles and documents

SUBSTITUTED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES

The present invention is directed to novel substituted aminopiperidines of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-?V enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.