1280211-40-6Relevant academic research and scientific papers
Application of optically active aminonaphthols as NMR solvating agents for chiral discrimination of mandelic acid
Chaudhary, Anju R.,Yadav, Priyanka,Bedekar, Ashutosh V.
, p. 767 - 774 (2014/06/09)
A series of optically active aminonaphthol derivatives were prepared and screened as chiral solvating agents to discriminate the CαH of racemic mandelic acid by 1H NMR analysis. An effort was made to establish a correlation of the structure of aminonaphthol derivatives and the selectivity in this non-covalent interaction. A linear relationship between the experimental and calculated enantiomeric purity was established by indicating the potential use of the system to determine the ee for the samples of mandelic acid of unknown enantiomeric purity.
Structural influence of chiral tertiary aminonaphthol ligands on the asymmetric phenyl transfer to aromatic aldehydes
Wei, Hui,Yin, Lu,Luo, Haibin,Li, Xingshu,Chan, Albert S. C.
, p. 222 - 227 (2012/03/27)
A series of chiral tertiary aminonaphthol ligands were prepared from 2-naphthol, (S)-1-phenylethylamine, and aldehydes with diverse substituted groups. The results of asymmetric phenyl transfer to aromatic aldehydes catalyzed by these chiral ligands indicated that enantioselectivities were greatly influenced by the electronic and steric effects of the ligands. Copyright
